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Found 3 Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 2' and Ligand = 'BDBM330042'
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330042((2S,5R,13aS)-N—((R)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330042((2S,5R,13aS)-N—((R)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330042((2S,5R,13aS)-N—((R)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  1.00E+4nMAssay Description:Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent