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Found 4 Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM275908'
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275908(US10071974, Example 19 | US10577336, Example 19)
Affinity DataKi:  194nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275908(US10071974, Example 19 | US10577336, Example 19)
Affinity DataKi:  194nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275908(US10071974, Example 19 | US10577336, Example 19)
Affinity DataEC50:  13.3nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275908(US10071974, Example 19 | US10577336, Example 19)
Affinity DataEC50:  13.3nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent