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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' and Ligand = 'BDBM313174'
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313174(US10166249, Example 689 | US10709719, Example 690 ...)
Affinity DataIC50:  1.70nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313174(US10166249, Example 689 | US10709719, Example 690 ...)
Affinity DataEC50:  5.70nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent