BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Steroid 5-alpha-reductase' and Ligand = 'BDBM50031877'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Steroid 5-alpha-reductase (Rattus norvegicus)	BDBM50031877 ((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Inc. Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compound				J Med Chem 38: 2621-7 (1995) Article DOI: 10.1021/jm00014a015 BindingDB Entry DOI: 10.7270/Q2C829XC
Glaxo Inc. Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Steroid 5-alpha-reductase (Rattus norvegicus)	BDBM50031877 ((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Inc. Research Institute Curated by ChEMBL					Assay Description Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2				J Med Chem 38: 2621-7 (1995) Article DOI: 10.1021/jm00014a015 BindingDB Entry DOI: 10.7270/Q2C829XC
Glaxo Inc. Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair