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Found 2 Enz. Inhib. hit(s) with Target = 'Stromelysin-1' and Ligand = 'BDBM13087'
TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM13087(CGS 27023A Analog 10 | N-hydroxy-2-[(2-methylpropy...)
Affinity DataKi:  5.35E+3nM ΔG°:  -31.3kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM13087(CGS 27023A Analog 10 | N-hydroxy-2-[(2-methylpropy...)
Affinity DataKi:  5.37E+3nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed