Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial' and Ligand = 'BDBM31068'
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM31068(2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...)
Affinity DataEC50:  749nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM31068(2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...)
Affinity DataEC50:  5.50E+3nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM31068(2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...)
Affinity DataEC50:  749nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent