Found 2 Enz. Inhib. hit(s) with Target = 'Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial' and Ligand = 'BDBM50231819' TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute Of Biological Sciences, Beijing
US Patent
National Institute Of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 5.01E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute Of Biological Sciences, Beijing
US Patent
National Institute Of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 817nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
