Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM280345'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  17.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  17.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  17.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  17.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent