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Found 2 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM20682'
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM20682(2-amino-6-methyl-5-[(4-nitrophenyl)methyl]-3H,4H,5...)
Affinity DataIC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

LigandPNGBDBM20682(2-amino-6-methyl-5-[(4-nitrophenyl)methyl]-3H,4H,5...)
Affinity DataIC50:  1.40E+4nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed