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Found 10 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50161779'
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataKi:  1.40E+3nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibitory constant against thymidylate synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Università

Curated by ChEMBL
LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibitory constant against thymidylate synthase from Escherichia coliMore data for this Ligand-Target Pair
TargetThymidylate synthase(Escherichia coli)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataKi:  1.80E+3nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibitory constant against human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  3.40E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  3.40E+3nMAssay Description:Affinity assay of specificities of thymidylate synthase (TS)inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  5.00E+3nMAssay Description:Affinity assay of specificities of thymidylate synthase (TS)inhibitorsMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  7.00E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  1.19E+5nMAssay Description:Affinity assay of specificities of thymidylate synthase (TS)inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed