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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue non-specific alkaline phosphatase (TNAP)' and Ligand = 'BDBM222188'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tissue non-specific alkaline phosphatase (TNAP)


(Bos taurus (Cattle))
BDBM222188
PNG
(6-(Dimethylamino)-3-(4'-hydroxy-3'-methoxy...)
Show SMILES COc1cc(ccc1O)C1NS(=O)(=O)c2cccc3c(ccc1c23)N(C)C
Show InChI InChI=1S/C20H20N2O4S/c1-22(2)15-9-8-14-19-13(15)5-4-6-18(19)27(24,25)21-20(14)12-7-10-16(23)17(11-12)26-3/h4-11,20-21,23H,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/a9.837



University of Karachi



Assay Description
Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...


Bioorg Chem 71: 10-18 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.008
BindingDB Entry DOI: 10.7270/Q26Q1W36
More data for this
Ligand-Target Pair