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Found 1 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM409981'
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409981(2-Amino-8-(2-phenyl-2,7-diazaspiro[3.5]nonane-7-ca...)
Affinity DataEC50:  7nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent