Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 9 (TLR9)' and Ligand = 'BDBM235721'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (TLR9) (Homo sapiens (Human))	BDBM235721 (US10117875, Example 63 | US9359361, 63) Show SMILES CN(C)CCN(C)c1nc(nc2nc(cnc12)N1CCN(C)CC1)-c1ccccc1 Show InChI InChI=1S/C22H30N8/c1-27(2)10-13-29(4)22-19-21(25-20(26-22)17-8-6-5-7-9-17)24-18(16-23-19)30-14-11-28(3)12-15-30/h5-9,16H,10-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu...				US Patent US10117875 (2018)
					More data for this Ligand-Target Pair
Toll-like receptor 9 (TLR9) (Homo sapiens (Human))	BDBM235721 (US10117875, Example 63 | US9359361, 63) Show SMILES CN(C)CCN(C)c1nc(nc2nc(cnc12)N1CCN(C)CC1)-c1ccccc1 Show InChI InChI=1S/C22H30N8/c1-27(2)10-13-29(4)22-19-21(25-20(26-22)17-8-6-5-7-9-17)24-18(16-23-19)30-14-11-28(3)12-15-30/h5-9,16H,10-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	37
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...				US Patent US9359361 (2016) BindingDB Entry DOI: 10.7270/Q2GH9GT3
					More data for this Ligand-Target Pair