BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Topoisomerase II alpha (HuTopoIIα)' and Ligand = 'BDBM50298277'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Topoisomerase II alpha (HuTopoIIα)


(Homo sapiens (Human))
BDBM50298277
PNG
(7-Chloro-[2-[(2-aminoethyl)methylamino]ethyl]anthr...)
Show SMILES CN(CCN)CCn1nc2-c3cccc(Cl)c3C(=O)c3cccc1c23
Show InChI InChI=1S/C19H19ClN4O/c1-23(9-8-21)10-11-24-15-7-3-5-13-17(15)18(22-24)12-4-2-6-14(20)16(12)19(13)25/h2-7H,8-11,21H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



University of Manitoba

Curated by ChEMBL


Assay Description
Inhibition of decatenation activity of human topoisomerase 2alpha


Bioorg Med Chem 17: 4575-82 (2009)

More data for this
Ligand-Target Pair