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Found 5 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50022307'
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50022307(CHEMBL3298242)
Affinity DataIC50:  84nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of allyl isothiocyanate-induced calcium flux incubated 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50022307(CHEMBL3298242)
Affinity DataIC50:  164nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50022307(CHEMBL3298242)
Affinity DataIC50:  252nMAssay Description:Antagonist activity at mouse TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50022307(CHEMBL3298242)
Affinity DataIC50:  400nMAssay Description:Antagonist activity at rat TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50022307(CHEMBL3298242)
Affinity DataIC50:  550nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of dibenzo[b,f ][1,4]oxazepine-4-carboxamide-induced calcium fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed