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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 2' and Ligand = 'BDBM50446559'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446559
PNG
(CHEMBL3110213)
Show SMILES CC(=O)c1cccc(c1)-c1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2OC(O)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C23H29N5O15P2/c1-9(29)10-3-2-4-11(5-10)20-27-14-19(24)25-8-26-21(14)28(20)22-17(32)15(30)12(41-22)6-39-44(35,36)43-45(37,38)40-7-13-16(31)18(33)23(34)42-13/h2-5,8,12-13,15-18,22-23,30-34H,6-7H2,1H3,(H,35,36)(H,37,38)(H2,24,25,26)/t12-,13-,15-,16-,17-,18-,22-,23?/m1/s1
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Similars

Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair