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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 2' and Ligand = 'BDBM50446560'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446560
PNG
(CHEMBL3110214)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4OC(O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)c(nc12)-c1ccsc1
Show InChI InChI=1S/C19H25N5O14P2S/c20-15-10-17(22-6-21-15)24(16(23-10)7-1-2-41-5-7)18-13(27)11(25)8(36-18)3-34-39(30,31)38-40(32,33)35-4-9-12(26)14(28)19(29)37-9/h1-2,5-6,8-9,11-14,18-19,25-29H,3-4H2,(H,30,31)(H,32,33)(H2,20,21,22)/t8-,9-,11-,12-,13-,14-,18-,19?/m1/s1
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Similars

Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair