Found 7 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50133817' TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka
Curated by ChEMBL
University Of Shizuoka
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of menthol-induced intracellul...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka
Curated by ChEMBL
University Of Shizuoka
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ accumula...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka
Curated by ChEMBL
University Of Shizuoka
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of menthol-induced increase in intracellular Ca2+ accumul...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka
Curated by ChEMBL
University Of Shizuoka
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of icilin-induced intracellula...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 475nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential b...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 475nMAssay Description:Antagonist activity at TRPM8 (unknown origin) assessed as reduction in menthol-induced calcium influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of TRPM8 (unknown origin)More data for this Ligand-Target Pair
