BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50231110'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50231110
PNG
(CHEMBL400779 | N-(1-(7-hydroxynaphthalen-1-yl)prop...)
Show SMILES CC(Cc1cccc2ccc(O)cc12)NC(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C21H18F3NO3/c1-13(11-16-4-2-3-14-5-8-17(26)12-19(14)16)25-20(27)15-6-9-18(10-7-15)28-21(22,23)24/h2-10,12-13,26H,11H2,1H3,(H,25,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 81n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cells


Bioorg Med Chem Lett 18: 1072-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.007
BindingDB Entry DOI: 10.7270/Q2PZ58K9
More data for this
Ligand-Target Pair