Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Found
1
Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM339942'
Target
Tryptophan 2,3-dioxygenase
(Homo sapiens (Human))
Iteos Therapeutics
US Patent
Ligand
BDBM339942
(6-fluoro-3-(6-(4- methylpiperazin-1-yl)pyridin- 3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 720nM
Assay Description:
The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI