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Found 1 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM339945'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iteos Therapeutics

US Patent
LigandPNGBDBM339945(N-(1-(5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)pipe...)
Affinity DataIC50:  970nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent