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Found 1 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM339958'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iteos Therapeutics

US Patent
LigandPNGBDBM339958(5-(6-fluoro-1H-indol-3-yl)-N- (2-(methylsulfonyl)e...)
Affinity DataIC50:  1.50E+3nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent