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Found
1
Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM347023'
Target
Tryptophan 2,3-dioxygenase
(Homo sapiens (Human))
Shanghai De Novo Pharmatech
US Patent
Ligand
BDBM347023
(US10202388, Compound 23A-3)
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Affinity Data
IC50: 300nM
Assay Description:
The TDO2 enzymatic assay was performed by UV absorption using a recombinant TDO2 and L-Tryptophan substrate. The UV absorption signal at 321 nm is co...
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Target Info
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Ligand Info
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US Patent
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