Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM50350281'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataKi:  2.10E+4nMAssay Description:Competitive inhibition of human purified TDO by Henri-Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human purified TDO assessed as initial rate of L-Trp oxidation at 100 uM of substrate concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50350281(CHEMBL1812527)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed