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Found 3 Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50145657'
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM50145657(CHEBI:47069 | CHEMBL412813)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of N-terminal MBP-tagged full length human TPH1 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microp...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM50145657(CHEBI:47069 | CHEMBL412813)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM50145657(CHEBI:47069 | CHEMBL412813)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TPH1 (unknown origin) using L-tyrosine as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed