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Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50205814'
TargetTyrosinase(Homo sapiens (Human))
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed