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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM202128'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202128(US9233983, G-2)
Affinity DataIC50:  5nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202128(US9233983, G-2)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202128(US9233983, G-2)
Affinity DataIC50:  54nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed