BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM264135'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (human))
BDBM264135
PNG
(2-(3-Bromo-2-methylphenyl)-5-methoxy-1H-pyrido[1,2...)
Show SMILES COc1cccn2c1cc(=O)n(-c1cccc(Br)c1C)c2=O
Show InChI InChI=1S/C16H13BrN2O3/c1-10-11(17)5-3-6-12(10)19-15(20)9-13-14(22-2)7-4-8-18(13)16(19)21/h3-9H,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, INVITROGEN Corporation), fluoresceinated peptide (1.5 μM), A...


US Patent US9714234 (2017)

More data for this
Ligand-Target Pair