Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM317627'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM317627(3-(4-{5- Amino-4-[4- (4-methyl- piperazine-1- carb...)
Affinity DataIC50:  39.1nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM317627(3-(4-{5- Amino-4-[4- (4-methyl- piperazine-1- carb...)
Affinity DataIC50:  39.1nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM317627(3-(4-{5- Amino-4-[4- (4-methyl- piperazine-1- carb...)
Affinity DataIC50:  39.1nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent