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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM389652'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM389652(6-(4-acryloylpiperazin-1-yl)-2-(4-phenoxyphenyl)py...)
Affinity DataIC50: <500nMAssay Description:1× and 2× assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM389652(6-(4-acryloylpiperazin-1-yl)-2-(4-phenoxyphenyl)py...)
Affinity DataIC50: <500nMAssay Description:The activity of the Examples and Analogs described herein, as inhibitors of BTK are demonstrated and confirmed by pharmacological in vitro assays. Ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM389652(6-(4-acryloylpiperazin-1-yl)-2-(4-phenoxyphenyl)py...)
Affinity DataIC50: <500nMAssay Description:1x and 2x assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM389652(6-(4-acryloylpiperazin-1-yl)-2-(4-phenoxyphenyl)py...)
Affinity DataIC50: <500nMAssay Description:1× and 2× assay buffer were made at first. BTK kinase was diluted with 1× assay buffer but substrate was diluted with 2× assay buffer. 1 ul of dilute...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent