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Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase FRK' and Ligand = 'BDBM13216'
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
University Court Of The University Of Edinburgh

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
University Court Of The University Of Edinburgh

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
University Court Of The University Of Edinburgh

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  0.310nMAssay Description:Binding constant for FRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
University Court Of The University Of Edinburgh

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  0.310nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
University Court Of The University Of Edinburgh

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  0.310nMAssay Description:Binding constant for FRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed