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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM340138'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))
BDBM340138
PNG
(US9758524, Example 27)
Show SMILES CCCc1ccnc(NC(=O)c2ccc(cc2OC)-c2nc([C@@H]3CCCCN3C(=O)\C=C\CN(C)C)n3ccnc(N)c23)c1
Show InChI InChI=1S/C33H40N8O3/c1-5-9-22-14-15-35-27(20-22)37-33(43)24-13-12-23(21-26(24)44-4)29-30-31(34)36-16-19-41(30)32(38-29)25-10-6-7-18-40(25)28(42)11-8-17-39(2)3/h8,11-16,19-21,25H,5-7,9-10,17-18H2,1-4H3,(H2,34,36)(H,35,37,43)/b11-8+/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+3n/an/an/an/a



Merck Sharp & Dohme B.V.

US Patent


Assay Description
FynT enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.FynT enzyme ...


US Patent US9758524 (2017)

More data for this
Ligand-Target Pair