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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM340147'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))
BDBM340147
PNG
(US9758524, Example 36)
Show SMILES CCCC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
Show InChI InChI=1S/C28H27N7O2/c1-2-3-4-10-23(36)34-17-7-8-21(34)27-33-24(25-26(29)31-16-18-35(25)27)19-11-13-20(14-12-19)28(37)32-22-9-5-6-15-30-22/h5-6,9,11-16,18,21H,2-3,7-8,17H2,1H3,(H2,29,31)(H,30,32,37)/t21-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+3n/an/an/an/a



Merck Sharp & Dohme B.V.

US Patent


Assay Description
FynT enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.FynT enzyme ...


US Patent US9758524 (2017)

More data for this
Ligand-Target Pair