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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM413456'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413456(9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitory activity of compounds against AURKA, AURKB, JAK1, JAK2 and JAK3 was determined in Z'-LYTEŽ assays run by ThermoFisher Scientific a...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413456(9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-...)
Affinity DataIC50: <1.00E+4nMAssay Description:The inhibitory activity of compounds against AURKA, AURKB, JAK1, JAK2 and JAK3 was determined in Z′-LYTEŽ assays run by ThermoFisher Scientific...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent