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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM103728'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  38.7nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  152nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  185nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of JAK2 in human whole blood assessed as inhibition of GM-CSF-induced pSTAT5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed