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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM116316'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM116316(US8637526, 277)
Affinity DataKi:  0.900nM ΔG°:  -51.1kJ/molepH: 7.2 T: 2°CAssay Description:To determine the inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 kinase reactions containing 0.2 nM purified JAK2 ...More data for this Ligand-Target Pair
In DepthDetails US Patent