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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM232736'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM232736(US9346815, 282 | US9604984, Example 282)
Affinity DataKi:  0.120nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM232736(US9346815, 282 | US9604984, Example 282)
Affinity DataKi:  0.120nM ΔG°:  -56.1kJ/molepH: 7.2 T: 2°CAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent