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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM234968'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent