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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM260508'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260508(US10428074, Example 114 | US9527851, 114 | US95278...)
Affinity DataIC50:  140nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260508(US10428074, Example 114 | US9527851, 114 | US95278...)
Affinity DataIC50:  140nMAssay Description:JAK2: In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260508(US10428074, Example 114 | US9527851, 114 | US95278...)
Affinity DataIC50:  140nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent