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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM264131'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM264131(3-(3-Bromo-2-methylphenyl)-8-methoxy-1-methylquina...)
Affinity DataIC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Compounds with activity against Jak2 tyrosine kinase have been observed to cause thrombocytopenia, anemia and neutropenia in human patients in clinic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent