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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM374721'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics

US Patent
LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)
Affinity DataKd:  0.570nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics

US Patent
LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)
Affinity DataKd:  0.570nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent