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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM449883'
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Leo Pharma
US Patent
Ligand
BDBM449883
(US10703751, Example 641 of WO2011086053)
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Affinity Data
EC50: 228nM
Assay Description:
Human baculovirus-expressed Janus kinase (JAK) 1, 2, 3 and tyrosin kinase (TYK) 2 were purchased from Carna Biosciences, Inc (#08-144, -045, -046, -1...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
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Ligand Info
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In Depth
Details
US Patent
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