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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [828-1132]' and Ligand = 'BDBM380448'
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM380448(4-{3-(Cyanomethyl)-3-[3′-(hydroxymethyl)-1H,...)
Affinity DataIC50: >700nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM380448(4-{3-(Cyanomethyl)-3-[3′-(hydroxymethyl)-1H,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent