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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM109873'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM109873(US8609647, 16)
Affinity DataIC50:  58nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM109873(US8609647, 16)
Affinity DataIC50:  58nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails US Patent