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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM195756'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM195756(US9206188, 7 | US9834551, Example 7)
Affinity DataIC50: <5nMAssay Description:1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM195756(US9206188, 7 | US9834551, Example 7)
Affinity DataIC50: <100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent