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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM234949'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Cadila Healthcare
US Patent
Ligand
BDBM234949
(4-(2-((4-([1,3'-bipyrrolidin]-1'-yl)phenyl)amino)p...)
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Affinity Data
IC50: 155nM
T: 2°C
Assay Description:
NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...
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Target Info
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Ligand Info
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