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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM260485'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260485(US10428074, Example 69 | US9527851, 69 | US9527851...)
Affinity DataIC50:  20nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK3 kinase. The test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260485(US10428074, Example 69 | US9527851, 69 | US9527851...)
Affinity DataIC50:  20nMAssay Description:JAK3: In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK3 kinase. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260485(US10428074, Example 69 | US9527851, 69 | US9527851...)
Affinity DataIC50:  20nMpH: 7.3 T: 2°CAssay Description:TBDIn vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK3 kinase. The te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent