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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM400813'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50:  38nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50:  56nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed