Found 7 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50161162' TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system using Ulight-Poly GT as ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:JAK3: The Omnia Assay Protocol for potency assessment against JAK3 was performed in a substantially similar manner as that described in Example 251 a...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly(4:1 Gl...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Chia Tai Tianqing Pharmaceutical Group
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
