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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50306682'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of human recombinant C-terminal hexahistidine tagged JAK3 JH1 catalytic domain (811 to 1124 residues) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  200nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed